Nasal decongestants: What They Do, Medicines
Nasal decongestants are drops or sprays that relieve a blocked nose by shrinking swollen blood vessels in the nose. They give quick relief but only for a few days. Longer use can make the blockage return or worsen (rebound congestion). Examples are xylometazoline and oxymetazoline.
Pharmacist review in progress. This page is based on the sources listed below and is being checked by our registered pharmacist.
How do Nasal decongestants work?
They tighten the small blood vessels in the lining of the nose, so the swelling goes down and air can pass more easily.
Active ingredients of this type
These active ingredients belong to Nasal decongestants. They are listed A to Z.
- Xylometazoline: Xylometazoline is a nasal decongestant, a medicine put in the nose to relieve a blocked nose from colds, hay fever and sinus problems.
Common questions
Why can nose sprays only be used for a few days?
Used for longer, they can make the nose more blocked once the effect wears off, called rebound congestion. UK regulator MHRA now limits xylometazoline and oxymetazoline sprays to five days. If you are still blocked after that, see a doctor or pharmacist.
Sources
- Recommended use of some nasal decongestant sprays limited to five days by UK regulator. GOV.UK (MHRA), 30 April 2026
- Otrivine Adult Nasal Drops (xylometazoline hydrochloride 0.1% w/v): patient information leaflet (revised 2/2024). Haleon UK, via the electronic medicines compendium (UK)
- ATC/DDD Index: R01A decongestants and other nasal preparations for topical use. WHO Collaborating Centre for Drug Statistics Methodology