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Selective serotonin reuptake inhibitors (SSRIs)

Also in: हिन्दी தமிழ் ਪੰਜਾਬੀ ଓଡ଼ିଆ অসমীয়া

SSRIs are prescription antidepressants used to treat depression and several anxiety conditions. Escitalopram is one example. They usually take a few weeks to work, and young people need close watching for mood changes early on. They should not be stopped suddenly, so any change is made with a doctor.

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How do Selective serotonin reuptake inhibitors (SSRIs) work?

SSRIs stop nerve cells from taking serotonin back up too quickly, so more of this chemical messenger stays available between nerve cells. Over some weeks this is linked with an improvement in mood and anxiety.

Active ingredients of this type

These active ingredients belong to Selective serotonin reuptake inhibitors (SSRIs). They are listed A to Z.

  • Escitalopram: Escitalopram is a prescription antidepressant used to treat depression and several anxiety conditions.
  • Sertraline: Sertraline is a prescription antidepressant of the SSRI group.

Common questions

Why do antidepressants carry a warning for young people?

Labels warn that antidepressants can increase suicidal thoughts and behaviour in children, teenagers and young adults, mostly early in treatment or after a dose change. Family or carers should watch for new or worsening mood changes and contact the doctor promptly.

Can I stop an SSRI suddenly?

No. Stopping suddenly can cause withdrawal symptoms such as dizziness, irritability and poor sleep. A doctor reduces the dose gradually. Do not stop on your own, even if you feel better.

How long does an SSRI take to work?

Often several weeks, so benefit may not be felt at first. Keep taking it as prescribed and tell your doctor about side effects or worries rather than stopping.

Sources

  1. Escitalopram: an antidepressant. NHS (UK)
  2. Lexapro (escitalopram) tablets and solution: prescribing information. DailyMed, US National Library of Medicine
  3. ATC/DDD Index: N06AB10 Escitalopram. WHO Collaborating Centre for Drug Statistics Methodology