Etoshine 90: Uses, How It Works, Side Effects
Also known as: Etoshine, Etoshine 90 mg, Etoshine 90 tablet, Etoricoxib 90 mg
Etoshine 90 is a prescription tablet containing 90 mg of etoricoxib, a COX-2 inhibitor used to relieve pain and inflammation in conditions such as rheumatoid arthritis, ankylosing spondylitis, osteoarthritis and acute gout, and for short-term pain after dental surgery. It can raise blood pressure and the risk of heart attack and stroke, and can irritate the stomach, so it is used at the lowest dose for the shortest time. It is taken once a day only on a doctor's prescription.
- Active ingredient
- Etoricoxib 90 mg
- Type of medicine
- COX-2 inhibitors (coxibs)
- Used for
- Joint pain and arthritis
- Starts working in
- Pain relief can begin within hours of a dose; the full effect in long-term joint conditions can take longer
- Effect lasts
- It is taken once a day
- With or without food
- Can be taken with or without food; follow the label or your doctor's advice
- Alcohol
- Alcohol raises the risk of stomach irritation and bleeding; ask your doctor
- Pregnancy
- No. It must not be used in pregnancy or breastfeeding; tell your doctor at once if you are or may be pregnant
- Habit-forming
- No
- Made by
- VERIFY on pack

Pharmacist review in progress. This page is based on the sources listed below and is being checked by our registered pharmacist.
On this page
- What is Etoshine 90 used for?
- How does Etoshine 90 work?
- How to take Etoshine 90
- Side effects of Etoshine 90
- Who should be careful
- Medicines and things that interact with Etoshine 90
- If someone takes too much
- Storage
- Regulatory status in India
- Other brands with the same medicine
- Other strengths and forms
- Common questions
What is Etoshine 90 used for?
Etoshine 90 is a prescription medicine. It is used, on a doctor's advice, to relieve pain and inflammation in certain joint conditions and for short-term pain after dental surgery.
- Relieving the symptoms of rheumatoid arthritis and ankylosing spondylitis
- Relieving the symptoms of osteoarthritis, when a doctor judges this strength suitable
- Relieving pain and inflammation in acute gout
- Short-term pain after dental surgery
How does Etoshine 90 work?
Etoricoxib mainly blocks the COX-2 enzyme, which makes the prostaglandins that cause pain, swelling and heat in inflamed joints. Because it acts less on COX-1, the enzyme that helps protect the stomach lining, it may upset the stomach less than some older NSAIDs, but it can still cause ulcers and bleeding.
What happens in your body after you take it
You swallow the tablet
The tablet is swallowed with water and etoricoxib is absorbed from the gut into the blood.
It travels in the blood
Etoricoxib is carried around the body and reaches inflamed joints and other tissues.
It blocks the COX-2 enzyme
Mainly in inflamed tissue, etoricoxib blocks the COX-2 enzyme that makes the prostaglandins responsible for pain, swelling and heat.
Pain and inflammation ease
With fewer prostaglandins, pain and swelling settle. The condition is not changed, only its symptoms are eased.
The body clears it
Etoricoxib is broken down, mainly in the liver, and removed from the body. It is taken once a day. It can still affect blood pressure, the kidneys and the stomach.
How to take Etoshine 90
Follow the label or your doctor's advice. Etoricoxib is taken once a day, and the strength that suits you depends on the condition. Your doctor decides the dose and for how long.
- Take Etoshine 90 exactly as your doctor has prescribed or as printed on the pack.
- It is taken once a day. Follow the label or your doctor's advice.
- It is used at the lowest dose that works for the shortest time.
- If you miss a dose, take it when you remember unless the next dose is nearly due. Do not take two doses together.
- Your doctor may check your blood pressure, kidney function and liver tests while you take it.
- If pain does not improve or gets worse, go back to your doctor.
Side effects of Etoshine 90
Most people take etoricoxib without serious problems. Some side effects are common and mild, but a few need medical help.
Uncommon or mild
- Swelling of the ankles or feet from fluid retention
- Dizziness or headache
- High blood pressure or a pounding heartbeat
- Heartburn, indigestion, stomach pain, nausea, constipation or diarrhoea
- Tiredness or weakness
- Easy bruising
Rare but serious: get medical help
- Black or bloody stools, vomiting blood or severe stomach pain (possible ulcer or bleeding). Get medical help at once
- Chest pain, breathlessness or weakness on one side of the body (possible heart attack or stroke). Call 112
- Swelling of the face, lips, tongue or throat, or difficulty breathing (severe allergic reaction). Call 112
- Skin rash, blistering or sores in the mouth (stop the medicine and see a doctor straight away)
- Yellow skin or eyes, dark urine or severe tiredness (possible liver problems)
- Sudden weight gain, swollen legs or passing much less urine (fluid retention, heart or kidney problems)
Who should be careful
Some people need to check with a doctor before taking etoricoxib, or need extra care while taking it.
When the label says not to use it
- Allergy to etoricoxib or any ingredient, or past asthma, rash or allergy after aspirin or an NSAID
- An active stomach ulcer or bleeding
- Heart failure, or high blood pressure that is not controlled
- Established heart disease, a past stroke or blocked leg arteries
- Severe liver or kidney disease, or inflammatory bowel disease
- Pregnancy or breastfeeding
- Under 16 years
- Heart and circulation: medicines of this group may raise the risk of heart attack and stroke; tell your doctor about heart disease, stroke, blood vessel disease, diabetes, high cholesterol or smoking
- Blood pressure: it can raise blood pressure, so it needs to be controlled first and checked regularly
- Stomach: ulcers and bleeding can happen, more often in older people, with a past ulcer, or with aspirin or other NSAIDs
- Kidney, liver or heart failure problems, or dehydration
- Asthma or allergy to aspirin or other NSAIDs
- Pregnancy and breastfeeding: not to be used
- It is not a replacement for aspirin if a doctor has prescribed aspirin to protect the heart
- It may hide a fever or other signs of infection
Medicines and things that interact with Etoshine 90
Etoricoxib can change how other medicines work, and some medicines change its effect. Tell your doctor or pharmacist about everything you take, including painkillers bought over the counter.
- Blood thinners such as warfarin: blood clotting tests may change and bleeding risk rises
- Blood pressure medicines, ACE inhibitors, ARBs and water tablets: they may work less well and the kidneys can be strained
- Aspirin: low-dose aspirin can be used together only if a doctor advises; the stomach risk rises
- Other NSAIDs: not recommended with etoricoxib
- Lithium: its blood level can rise
- Methotrexate: its blood level can rise
- Oral contraceptives and hormone replacement: their hormone levels can rise
- Rifampicin: can make etoricoxib work less well
If someone takes too much
Taking more than prescribed can cause stomach pain, nausea, vomiting, high blood pressure and kidney or liver problems. If someone has taken more than the label says, call 112 or go to the nearest hospital and take the medicine pack with you.
Storage
Store below 30 C in a dry place, protected from light and moisture, in the original strip, and out of the reach of children. Do not use after the expiry date. Check the pack for the exact storage instructions.
Regulatory status in India
Approved for sale in India as a prescription medicine. Etoshine 90 contains etoricoxib only. Single-ingredient etoricoxib is not on the CDSCO list of medicines banned under section 26A of the Drugs and Cosmetics Act. Etoricoxib was not found in the Schedule H text of the Drugs Rules 1945, so the schedule printed on the pack should be checked.
Other brands with the same medicine
Etoricoxib 90 mg tablets are sold under other brand names and as generic medicines. They contain the same medicine; check the label for the strength. Etoricoxib is also sold in other strengths, and the right strength depends on the condition, so do not switch without asking your doctor.
Other strengths and forms
Etoricoxib is sold in other strengths, and some products combine it with other medicines. The strength and contents are printed on the pack and differ between products, so check the label of the one you have.
Common questions
Is Etoshine 90 a prescription medicine?
Yes, it should be taken only if a doctor has prescribed it. Etoricoxib raises the risk of heart, blood pressure and stomach problems in some people, so do not start, stop or change it without the doctor's advice.
What is Etoshine 90 used for?
It is used to relieve symptoms in rheumatoid arthritis, ankylosing spondylitis and, when a doctor judges it suitable, osteoarthritis, acute gout and short-term pain after dental surgery. It eases symptoms and does not treat the cause of the disease.
Can Etoshine 90 raise blood pressure?
Yes. Etoricoxib can raise blood pressure and cause fluid retention. Blood pressure should be controlled before starting and checked regularly. Tell your doctor about swollen ankles, chest pain or breathlessness.
Is Etoshine 90 safer for the stomach than other painkillers?
It may upset the stomach less than some older NSAIDs, but it can still cause ulcers and bleeding, especially with aspirin or other NSAIDs. It also has heart and blood pressure risks, so it is not suitable for everyone.
Can I take Etoshine 90 during pregnancy?
No. Etoricoxib must not be used in pregnancy or breastfeeding. If you are pregnant, may become pregnant or are breastfeeding, tell your doctor right away.
What is the difference between Etoshine 90 and Etoricoxib 90 mg?
Etoshine is a brand name and etoricoxib is the medicine inside it. Generic etoricoxib 90 mg tablets contain the same active ingredient. Check the strength on the pack and ask your doctor before switching products.
Sources
- Arcoxia 90 mg film-coated tablets: Summary of Product Characteristics. electronic medicines compendium (emc), UK
- ATC/DDD Index: M01AH05 Etoricoxib. WHO Collaborating Centre for Drug Statistics Methodology
- List of drugs prohibited for manufacture and sale through gazette notifications under section 26A of the Drugs & Cosmetics Act 1940. Central Drugs Standard Control Organisation (CDSCO)
- The Drugs Rules, 1945 (consolidated, September 2024 edition), Schedule H: prescription drugs. Central Drugs Standard Control Organisation (CDSCO)
