Tryptomer 10: Uses, How It Works, Side Effects
Also known as: Tryptomer, Tryptomer 10 mg, Tryptomer 10 tablet, Amitriptyline 10 mg
Tryptomer 10 is a prescription tablet containing 10 mg of amitriptyline, a tricyclic antidepressant used to relieve the symptoms of depression. It usually takes some weeks to work. It can cause drowsiness, dry mouth and heart rhythm effects, and an overdose can be dangerous. It must not be stopped suddenly, and young people need close watching for mood changes early in treatment.
- Active ingredient
- Amitriptyline 10 mg
- Type of medicine
- Tricyclic antidepressants
- Used for
- Depression
- Starts working in
- Full benefit can take several weeks; drowsiness can be felt sooner
- Effect lasts
- Taken daily, usually for months; the doctor decides how long
- With or without food
- Can be taken with or without food; follow the label or your doctor's advice
- Alcohol
- Best avoided; alcohol adds to drowsiness
- Pregnancy
- Only if the doctor judges the benefit outweighs the risk; tell your doctor if you are pregnant, plan a baby or are breastfeeding
- Habit-forming
- Not addictive, but do not stop suddenly because it can cause withdrawal symptoms
- Made by
- VERIFY on pack
Pharmacist review in progress. This page is based on the sources listed below and is being checked by our registered pharmacist.
On this page
- What is Tryptomer 10 used for?
- How does Tryptomer 10 work?
- How to take Tryptomer 10
- Side effects of Tryptomer 10
- Who should be careful
- Medicines and things that interact with Tryptomer 10
- If someone takes too much
- Storage
- Regulatory status in India
- Other brands with the same medicine
- Other strengths and forms
- Common questions
What is Tryptomer 10 used for?
Tryptomer 10 is a prescription medicine. It is used, on a doctor's advice, to relieve the symptoms of depression.
- Relieving the symptoms of depression in adults
How does Tryptomer 10 work?
Serotonin and noradrenaline are chemical messengers in the brain that are linked to mood. Amitriptyline is thought to stop nerve cells from taking them back up, so more of them stay available between nerve cells. The exact way it works is not fully known.
What happens in your body after you take it
You swallow the tablet
The tablet dissolves in the gut and amitriptyline is absorbed into the blood. It can be taken with or without food.
It travels in the blood
Amitriptyline is carried around the body and reaches the brain.
It blocks reuptake
In the brain, amitriptyline is thought to block the pumps that pull serotonin and noradrenaline back into the nerve cell.
More messengers stay available
With the pumps blocked, more of these messengers remain between nerve cells. Over some weeks, mood can improve. It also blocks other body signals, which is why drowsiness and dry mouth are common.
The body clears it
The liver breaks amitriptyline down and it leaves the body over time. Stopping suddenly can cause withdrawal symptoms, so any change is made with a doctor.
How to take Tryptomer 10
Take Tryptomer 10 exactly as your doctor has prescribed or as printed on the pack. Your doctor decides the dose, when to change it and how long you need it.
- Doctors usually start with a low dose and raise it slowly. Never raise the dose yourself.
- It is taken at about the same time each day. Follow the label or your doctor's advice about when, since it can cause drowsiness.
- If you miss a dose, take it when you remember. If it is almost time for the next dose, skip the missed one. Do not take two doses together.
- It can take several weeks to work. Keep taking it as prescribed and tell your doctor about any worries.
- Do not stop taking it on your own, even if you feel better. Stopping suddenly can cause withdrawal symptoms; your doctor lowers the dose gradually.
Side effects of Tryptomer 10
Many side effects are mild, but amitriptyline can affect the heart and some effects need medical help.
Uncommon or mild
- Drowsiness, tiredness or dizziness
- Dry mouth
- Constipation
- Blurred vision
- Difficulty passing urine
- Weight or appetite changes
- Fast heartbeat or sweating
Rare but serious: get medical help
- New or worse low mood, or thoughts of harming yourself. Get help at once
- Chest pain, fainting, or a fast or irregular heartbeat
- Seizures, confusion or hallucinations
- Eye pain or vision changes
- Yellow skin or eyes, or unusual bleeding or bruising
- Swelling of the face, lips or throat, or a severe rash. Get medical help immediately
Who should be careful
Some people need to check with a doctor before taking Tryptomer 10, or need extra care while taking it.
When the label says not to use it
- Taking an MAOI antidepressant, or within 14 days of stopping one
- Taking cisapride
- In the recovery period soon after a heart attack
- Allergy to amitriptyline or any ingredient
- Children, teenagers and young adults: antidepressants can increase suicidal thoughts and behaviour. The label says amitriptyline is not approved for use in children. Family and carers should watch for new or worse mood, agitation or restlessness and tell the doctor promptly
- Do not stop suddenly: this can cause nausea, headache and feeling unwell. Your doctor lowers the dose gradually
- Heart disease, or a recent heart attack
- Epilepsy or seizures
- Glaucoma, an enlarged prostate or trouble passing urine
- Bipolar disorder or past mania
- Liver disease or an overactive thyroid
- Older adults: more likely to have dizziness, falls and confusion, so extra care is needed
- Driving: it can cause drowsiness, so take care until you know how it affects you; alcohol adds to this
- Pregnancy and breastfeeding: talk to your doctor before use
- Surgery or dental work: tell the doctor or dentist that you take it
Medicines and things that interact with Tryptomer 10
Tryptomer 10 can change how other medicines work, and some medicines change its effect. Tell your doctor or pharmacist about everything you take, including herbal remedies and cold or allergy medicines bought over the counter.
- MAOI antidepressants: must not be combined; a gap of at least 14 days is needed after stopping an MAOI
- Cisapride: must not be combined
- Other medicines that raise serotonin (SSRIs, tramadol, triptans, lithium, St John's wort): risk of serotonin syndrome
- Some SSRIs (such as fluoxetine or paroxetine), cimetidine and quinidine: they can raise the amount of amitriptyline in the blood
- Alcohol, sleeping tablets and other sedatives: more drowsiness
If someone takes too much
An overdose of amitriptyline can be fatal. It can seriously affect the heart and cause seizures and loss of consciousness. If someone has taken more than prescribed, call 112 or go to the nearest hospital at once and take the medicine pack with you.
Storage
Store below 30 C in a dry place, protected from light and moisture, in the original strip, and out of the reach of children. Do not use after the expiry date. Check the pack for the exact storage instructions.
Regulatory status in India
Approved for sale in India as a prescription medicine. Single-ingredient amitriptyline was not found on the CDSCO list of medicines banned under section 26A of the Drugs and Cosmetics Act in this check; the reviewer should confirm. Tryptomer 10 contains amitriptyline only.
Other brands with the same medicine
Amitriptyline 10 mg tablets are sold under other brand names and as generic medicines. They contain the same medicine; check the label for the strength. Some products contain other medicines too, so do not switch between them without asking your doctor.
Other strengths and forms
Amitriptyline is sold in different strengths. The strength and contents are printed on the pack and are not the same across products, so check the label of the one you have.
Common questions
Is Tryptomer 10 a prescription medicine?
Yes. Amitriptyline is a prescription-only medicine in India. It should be taken only if a doctor has prescribed it, and it should not be started, stopped or changed without the doctor's advice.
How long does Tryptomer 10 take to work?
Full benefit can take several weeks, so keep taking it as prescribed even if you feel no change at first. Tell your doctor about side effects or worries rather than stopping.
Can I stop Tryptomer 10 suddenly?
No. Stopping suddenly can cause nausea, headache and low energy. A doctor lowers the dose gradually. Do not stop on your own, even if you feel better.
Why is there a warning for young people?
Antidepressant labels warn of more suicidal thoughts in children, teenagers and young adults, mostly early in treatment or after dose changes. Families should watch for new or worsening mood changes and contact the doctor promptly.
What should I do if I have thoughts of harming myself?
Get help immediately: call 112 or go to the nearest hospital, or tell a trusted person. Tele-MANAS (14416) is a free mental health helpline in India. Tell your doctor if your mood worsens after starting a medicine.
Is an overdose of Tryptomer 10 dangerous?
Yes. Too much amitriptyline can seriously affect the heart and can be fatal, even in small excess for children. Keep tablets out of reach and call 112 or go to the nearest hospital at once if too much is taken.
Will Tryptomer 10 make me drowsy?
It often does. Take care when driving or using machines until you know how it affects you, and avoid alcohol, which adds to drowsiness. Follow the label or your doctor's advice about when to take it.
What is the difference between Tryptomer 10 and amitriptyline 10 mg?
Tryptomer is a brand name, and amitriptyline is the medicine inside it. Generic amitriptyline 10 mg tablets contain the same active ingredient. Check the strength and ingredients on the pack, and ask your doctor before switching products.
Sources
- Amitriptyline hydrochloride tablet, film coated: prescribing information (Sun Pharmaceutical Industries). DailyMed, US National Library of Medicine
- Amitriptyline. MedlinePlus, US National Library of Medicine
- Depression in adults. NHS (UK)